The Alzheimer’s drug being tested by Penn Medicine has been approved by the Food and Drug Administration

Campus Penn Medicine on October 3, 2020. Credit: Max Mester The Federal Drug Administration recently approved a drug being trialled by the Penn Memory Center to reduce the risk of Alzheimer’s disease. The drug, Leqembi, won FDA approval under the accelerated approval pathway on January 6, after the AHEAD trial evaluating its efficacy in volunteers … Read more

Using deep brain stimulation to treat symptoms of Alzheimer’s disease

One of the most innovative medical developments of the 21st century – deep brain stimulation (DBS) – has allowed doctors to target specific regions of the brain and treat conditions such as dystonia, epilepsy, idiopathic tremor, Parkinson’s disease and obsessive-compulsive disorder. This neurosurgical procedure involves implanting electrodes that generate impulses that control abnormal brain activity. … Read more

New nanoparticles provide treatment at the brain level and unlock the Alzheimer’s gene

summary: Researchers have developed a new family of nanocapsules that are able to carry CRISPR gene-editing tools to different organs of the body before they degrade harmlessly. The capsules were able to enter the brains of mice and successfully edit a gene associated with Alzheimer’s disease. Source: University of Wisconsin-Madison Gene therapies have the potential … Read more

Exposure to World Trade Center dust exacerbates cognitive impairment in an animal model of Alzheimer’s disease

summary: Mice exposed to WTC dust showed impairments in both long- and short-term memory, and spatial recognition, as well as alterations in genes associated with the inflammatory immune response and blood-brain barrier dysfunction. The results indicate that first responders exposed to dust from the World Trade Center experience a peripheral brain immune inflammatory response that … Read more

How 6 minutes of exercise can delay Alzheimer’s and Parkinson’s disease

According to a new study, just six minutes of high-intensity exercise can extend the life of a healthy brain and delay the onset of neurodegenerative disorders such as Alzheimer’s and Parkinson’s. The research found that a short but intense bout of cycling increases production of a protein essential for brain formation, learning and memory, and … Read more

Hormone replacement therapy can prevent Alzheimer’s disease among women at risk

summary: Use of hormone replacement therapy (HRT) has been associated with improved cognition, memory and larger brain volume in women who carry the APOE4 genetic variant associated with Alzheimer’s disease. Source: University of East Anglia Hormone replacement therapy (HRT) can help prevent Alzheimer’s dementia among women at risk of developing the disease – according to … Read more

Alzheimer’s Drug Discovery Foundation and Har

Image: Studies have shown that physical activity, especially endurance exercise, can improve cognitive function in part by reducing inflammation in the brain. Dr. Ran focused on finding out why this happened and how this could be translated into an effective treatment for Alzheimer’s patients. Opinion more Credit: Harrington Discovery Institute at University Hospitals Cleveland–The Alzheimer’s … Read more